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Fibronectin receptor subunit (α5, α4 and β1) mRNA and cell surface expression in human peripheral blood B lymphocytes

✍ Scribed by Fred R. Kohn; Michael E. Grigg; Hans-G. Klingemann


Book ID
104177432
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
331 KB
Volume
28
Category
Article
ISSN
0165-2478

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Cytofluorimetric and reverse-transcription polymerase chain reaction (RT-PCR) analysis showed that adriamycinresistant (ADR R ), but not sensitive (WT), MCF-7 human mammary carcinoma cell lines express a4b1 and a5b1 integrins. ADR R cells adhere to fibronectin (FN), and only a5b1 is involved in cell