We have recently described a 550,000-dalton nomollagenous cartilage matrix glycoprotein (CMGP), with subunits of 130,000, which is present in hyaline cartilage and fibrocartilage. Biosynthetic studies indicated that CMGP was synthesized by short-term organ cultures of normal canine articular cartila
Fibronectin in osteoarthritic canine articular cartilage
β Scribed by Nancy B. Wurster; George Lust
- Book ID
- 115756141
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 561 KB
- Volume
- 109
- Category
- Article
- ISSN
- 0006-291X
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π SIMILAR VOLUMES
The purpose of this study was to determine if articular cartilage was able to accumulate fibronectin, a large molecule of 440,000 daltons, from the external medium, and if so, to compare the extent of accumulation by normal and osteoarthritic cartilage and to localize the sites of fibronectin accumu
## Abstract Osteoarthritis (OA) is associated with increased levels of reactive oxygen species. This study investigated if increased oxidative DNA damage accumulates in OA articular cartilage compared with nonβOA articular cartilage from pigs with spontaneous OA. Additionally, the ability of nitric