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Fibronectin and collagen inhibit cell-substratum adhesion of neutrophil granulocytes

✍ Scribed by A.F. Brown; J.M. Lackie

Book ID
115891414
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
527 KB
Volume
136
Category
Article
ISSN
0014-4827

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Human megakaryoblastic leukemia Meg-01 cells were attached to fibronectin (FN)-coated substratum, on which remarkable spreading and cytoplasmic elongation was induced by treatment with a protein kinase inhibitor, staurosporine (stp). This effect was inhibited by RGDS and was also not seen on FN-lack