Fibronectin and Cell Attachment to Cell and Protein Resistant Polyelectrolyte Surfaces
β Scribed by Olenych, Scott G.; Moussallem, Maroun D.; Salloum, David S.; Schlenoff, Joseph B.; Keller, Thomas C. S.
- Book ID
- 126193726
- Publisher
- American Chemical Society
- Year
- 2005
- Tongue
- English
- Weight
- 439 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1525-7797
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
To better understand the events involved in the generation of defined tissue architectures on biomaterials, we have examined the mechanism of attachment of human bone-derived cells (HBDC) to surfaces with patterned surface chemistry in vitro. Photolithography was used to generate alternating domains
Fibronectin possesses a domain that interacts with cell surfaces. The ability of fibronectin to promote cell attachment can be duplicated with a short amino acid sequence, glycyl-L-arginyl-glycyl-L-aspartyl-L-serine, taken from that domain. The tripeptide Arg-Gly-Asp appears to be irreplaceable for