Fibroblast growth factor can substitute for platelet factor to sustain the growth of BALB/3T3 cells in the presence of plasma
✍ Scribed by D. Gospodarowicz; G. Greene; J. Moran
- Book ID
- 119405931
- Publisher
- Elsevier Science
- Year
- 1975
- Tongue
- English
- Weight
- 357 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0006-291X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Platelet‐derived growth factor (PDGF) and platelet‐poor plasma, which lacks PDGF, both induce a rapid increase in the rate of total protein synthesis within quiescent, density‐arrested Balb/c‐3T3 cells. This stimulation of protein synthesis is associated with an increased aggregation of
## Abstract Much controversy regarding the relationship between nutrients and serum in regulation of cell growth can be reconciled by recognizing that serum contains multiple factors which regulate different events in the cell cycle. Serum was fractioned into a platelet‐derived growth factor (PDGF)
## Abstract The platelet‐derived growth factor (PDGF), which is found in serum but not in plasma, has been purified to homogeneity; it stimulates replication at a concentration of 10^−10^M. Brief treatment with PDGF causes densityinhibited Balb/c‐3T3 cells to become competent to synthesize DNA; pit
## Abstract Benzo[a]pyrene‐transformed Balb 3T3 cells (BP3T3) exhibit “normal” growth controls at low concentrations of serum. Epidermal growth factor (EGF) stimulates DNA synthesis and cell division in both Balb 3T3 and BP3T3 cells at physiological concentrations. The growth response of BP3T3 cell