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Fibroblast Growth Factor-2 Induces Lef/Tcf-dependent Transcription in Human Endothelial Cells

✍ Scribed by Holnthoner, W.


Book ID
121827737
Publisher
The American Society for Biochemistry and Molecular Biology
Year
2002
Tongue
English
Weight
742 KB
Volume
277
Category
Article
ISSN
0021-9258

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Vascular endothelial growth factor (VECF) is a 45kDa secreted peptide that has potent mitogenic activity specific for endothelial cells in vitro and the ability to induce a strong angiogenic response in vivo. In the present study, 24 h treatment with VEGF resulted in a stimulation of expression of t