Mutations in the fibrinogen gene cluster
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Marguerite Neerman-Arbez; Philippe de Moerloose
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Article
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2007
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John Wiley and Sons
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English
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## Communicated by Arupa Ganguly Fibrinogen is synthesized in hepatocytes in the form of a hexamer composed of two sets of three polypeptides (Aa, Bb, and c). Each polypeptide is encoded by a distinct gene, FGA, FGB, and FGG, all three clustered in a region of 50 kb on 4q31. Congenital afibrinogen