Binding of fibrinogen to platelet integr
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Germán Rivas; Kirsten Tangemann; Allen P. Minton; Jürgen Engel
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Article
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1996
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John Wiley and Sons
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English
⚖ 864 KB
Fibrinogen showed essentially no binding (KD> 1 mM) to platelet aIIb@ integrin in solution in the presence of Triton or octylglucoside above critical micellar concentrations. Under these conditions the integrin was an a$ monomer. After removal of the detergent from the Triton containing buffer (25 m