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fibrin glue for sealing the needle track in fine-needle percutaneous lung biopsy using a coaxial system: Part II—clinical study

✍ Scribed by Theodore Petsas; Dimitris Siamblis; Costas Giannakenas; Kostas Tepetes; Dimitris Dougenis; Kostas Spiropoulos; Ioannis Fezoulidis; Ioannis Dimopoulos


Book ID
104729340
Publisher
Springer
Year
1995
Tongue
English
Weight
968 KB
Volume
18
Category
Article
ISSN
1432-086X

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✦ Synopsis


Purpose:

Following percutaneous lung biopsy (plb), we used fibrin glue as a sealant in 26 patients for the purpose of decreasing the incidence of pneumothorax.

Methods:

All 26 patients (group a) had chronic obstructive pulmonary disease (copd). the results for group a were compared with a control group of 32 patients (group b), also with copd and in whom fibrin glue was not used. all biopsies were conducted under computed tomography (ct) using a coaxial needle system consisting of 19-gauge and 22-gauge needles.

Results:

Pneumothorax developed in five patients (19.2%) in group a and in one instance, drainage was required (3.8%). in group b, pneumothorax developed in 13 patients (40.6%) and in six instances (18.8%) drainage was required. comparing the use of chest-tube drainage in the two groups, a statistical significance was observed, p < 0.0025). no adverse reactions related to the fibrin glue were observed.

Conclusion:

Our results indicate that fibrin glue is a safe sealing material for lung plb and serves to decrease the incidence and, in particular, the severity of pneumothorax, especially in high-risk patients.