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Fibrils from brains of cows with new cattle disease contain scrapie-associated protein

✍ Scribed by Hope, James; Reekie, Laura J. D.; Hunter, Nora; Multhaup, Gerd; Beyreuther, Konrad; White, Heather; Scott, Anthony C.; Stack, Michael J.; Dawson, Michael; Wells, Gerald A. H.

Book ID: 109757160
Publisher: Nature Publishing Group
Year: 1988
Tongue: English
Weight: 424 KB
Volume: 336
Category: Article
ISSN: 0028-0836
DOI: 10.1038/336390a0

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Chronic wasting disease (CWD), a progressive, fatal neurological disorder of captive mule deer and Rocky Mountain elk, is characterized neuropathologically by spongiform change in the neuropil, intraneuronal vacuolation and astrocytic hypertrophy and hyperplasia. Recently, scrapie amyloid-immunoreac