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Fibrillary co-deposition of laminin-5 and large unspliced tenascin-C in the invasive front of oral squamous cell carcinoma in vivo and in vitro

✍ Scribed by Alexander Berndt; Laura Borsi; Peter Hyckel; Hartwig Kosmehl


Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
443 KB
Volume
127
Category
Article
ISSN
1432-1335

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The inclusion or omission of the alternatively spliced region in the tenascin-C (Tn-C) mRNA gives rise to the large (Tn-C L ) or small (Tn-C S ) variant, respectively. Tn-C L is thought to be a typical component of provisional extracellular matrices (ECMs) and is expressed during tumour stroma remod