Fibre-laser IR luminescence diagnostics of malignant tumours using rare earth porphyrins

✍ Scribed by M.I. Gaiduk; V.V. Grigoryants; A.F. Mironov; V.D. Rumyantseva; V.I. Chissov; G.M. Sukhin

• Book ID: 103993120
• Publisher: Elsevier Science
• Year: 1990
• Tongue: English
• Weight: 352 KB
• Volume: 7
• Category: Article
• ISSN: 1011-1344
• DOI: 10.1016/1011-1344(90)85139-n

✦ Synopsis

To eliminate the masking effect of the background luminescence of endogenic substances in biological tissues and to increase the luminescence contrast values of malignant tumours, sarcoma-implanted mice were administered with ytterbium porphyrins instead of free porphyrin radicals. This was followed by in vivo luminescence localization of tumours using fibre-laser spectrofluorometry. The luminescence contrast values obtained reached 10-45 which is evidently not a limit.