Fialuridine toxicity
โ Scribed by R Schmid
- Book ID
- 102244028
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 98 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
โฆ Synopsis
ICAM-1 in control human or mouse liver. 5,6 In contrast, vari-cytes were present in large numbers in the sinusoids. 10 In conclusion, we still think that the enhanced ICAM-1 expresous other reports only observed an in situ staining of ICAMsion on PC can contribute to the influx of leukocytes during 1 on sinusoidal liver cells and no staining of the parenchymal sepsis. liver cells (e.g., [7][8][9] ). It should be noted that using a more qualitative method, such as peroxidase immunostaining, may MARIJKE VAN OOSTEN, Ph.D. make it more hard to detect a low expression of ICAM-1 on JOHAN KUIPER, Ph.D. parenchymal liver cells, especially when in the same sections Division of Biopharmaceutics (LACDR) the expression of ICAM-1 on sinusoidal cells is more pro-University of Leiden nounced. Our method using iodinated anti-ICAM-1 may be Leiden, The Netherlands more appropriate in order to determine the expression levels of ICAM-1 quantitatively. The previously mentioned publica-
๐ SIMILAR VOLUMES
Woodchucks were used to study the antiviral activity and toxicity of fialuridine (FIAU; 1,-2'deoxy-2'fluoro-1-beta-D-arabinofuranosyl-5-iodo-uracil). In an initial experiment, groups of six chronic woodchuck hepatitis virus (WHV) carrier woodchucks received daily doses of FIAU by intraperitoneal inj