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Fhl2 deficiency results in osteopenia due to decreased activity of osteoblasts

✍ Scribed by Günther, Thomas; Poli, Cecilia; Müller, Judith M; Catala-Lehnen, Philip; Schinke, Thorsten; Yin, Na; Vomstein, Sandra; Amling, Michael; Schüle, Roland


Book ID
110031165
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
328 KB
Volume
24
Category
Article
ISSN
0261-4189

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The mitochondrial trifunctional protein (TFP) is an enzyme complex of the fatty acid beta-oxidation cycle composed of an alpha- and a beta-subunit. The two encoding genes are located in the same region on chromosome 2 (2p23). TFP deficiency due to either alpha- or beta-subunit mutations is character