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FHL-1/reconectin and factor H: two human complement regulators which are encoded by the same gene are differently expressed and regulated

✍ Scribed by Manuel A Friese; Jens Hellwage; T.Sakari Jokiranta; Seppo Meri; Hans H Peter; Hermann Eibel; Peter F Zipfel


Book ID
117326621
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
199 KB
Volume
36
Category
Article
ISSN
0161-5890

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The CYP1 gene has previously been identified as coding for a positive trans active factor that activates the expression of CYC1 and CYP3, which are the structural genes for isol-and iso2-cytochrome c. Two phenotypically distinct classes of CYP1 mutations can be obtained indicating that CYC1 and CYP3