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FHITGene Sequence Variants and Reduced Fhit Protein Expression in Glioblastoma Multiforme

✍ Scribed by Gulsah Cecener; Berrin Tunca; Unal Egeli; Ahmet Bekar; Gulnur Guler; Sahsine Tolunay; Kaya Aksoy


Book ID
118298033
Publisher
Springer
Year
2009
Tongue
English
Weight
347 KB
Volume
30
Category
Article
ISSN
0272-4340

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## Abstract ## BACKGROUND. Regions of hypoxia within glioblastoma multiforme (GBM) are common and may influence a tumor's aggressiveness, response to treatment, and the patient's overall survival. In this study, the authors examined 4 markers of hypoxia (hypoxia‐inducible factor 1 [HIF‐1Ξ±], glucos