Fgfrl1, a fibroblast growth factor receptor-like gene, is found in the cephalochordate Branchiostoma floridae but not in the urochordate Ciona intestinalis

Fusion of the BCR and the fibroblast gro

Fusion of the BCR and the fibroblast growth factor receptor-1 (FGFR1) genes as a result of t(8;22)(p11;q11) in a myeloproliferative disorder: The first fusion gene involving BCR but not ABL

✍ Thoas Fioretos; Ioannis Panagopoulos; Carin Lassen; Agneta Swedin; Rolf Billströ 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 305 KB

## Abstract Constitutive activation of tyrosine kinases as a consequence of chromosomal translocations, forming fusion genes, plays an important role in the development of hematologic malignancies, in particular, myeloproliferative syndromes (MPSs). In this respect, the t(9;22)(q34;q11) that result