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FGFR3 mutation affects cell growth, apoptosis and attachment in keratinocytes

✍ Scribed by Christian Hafner; Erica Di Martino; Eva Pitt; Thomas Stempfl; Darren Tomlinson; Arndt Hartmann; Michael Landthaler; Margaret Knowles; Thomas Vogt


Book ID
113956011
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
515 KB
Volume
316
Category
Article
ISSN
0014-4827

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Identification of FGFR3 mutations in 28 achondroplasia patients, in 10 of 18 cases of hypochodroplasia and in both cases with type I TD, is reported here. To detect mutations of achondroplasia, both natural restriction site and amplification created restriction site (ACRS) were utilized. Mutation 11