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FGFR2 signaling in normal andlimbless chick limb buds

✍ Scribed by Lizarraga, Gail ;Ferrari, Deborah ;Kalinowski, Michael ;Ohuchi, Hideyo ;Noji, Sumihare ;Kosher, Robert A. ;Dealy, Caroline N.

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 398 KB
Volume: 25
Category: Article
ISSN: 0192-253X
DOI: 10.1002/(sici)1520-6408(1999)25:4<331::aid-dvg7>3.0.co;2-u

No coin nor oath required. For personal study only.

✦ Synopsis

FGF10 and FGF8, which are reciprocally expressed by the mesoderm and AER of the developing limb bud, have been implicated in limb initiation, outgrowth, and patterning. FGF10 and FGF8 signal through the FGFR2b and FGFR2c alternative splice isoforms, respectively [

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