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FGFR1 expression and gene copy numbers in human lung cancer

✍ Scribed by Kohler, Lukas H.; Mireskandari, Masoud; Knösel, Thomas; Altendorf-Hofmann, Annelore; Kunze, Almut; Schmidt, Andreas; Presselt, Norbert; Chen, Yuan; Petersen, Iver


Book ID
113042279
Publisher
Springer
Year
2012
Tongue
English
Weight
776 KB
Volume
461
Category
Article
ISSN
1432-2307

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## Abstract Activation of oncogenic __Kras__ in murine lung leads to the development of numerous small adenomas, only some of which progress over time to overt adenocarcinoma. Thus, although __Kras__ is the initiating oncogene, it is likely that secondary genetic events are required for progression