Few associations of candidate genes with nonsyndromic orofacial clefts in the population of Lithuania
✍ Scribed by Aušra Morkūnienė; Danguolė Steponavičiūtė; Algirdas Utkus; Vaidutis Kučinskas
- Book ID
- 105732791
- Publisher
- Springer-Verlag
- Year
- 2007
- Tongue
- English
- Weight
- 65 KB
- Volume
- 48
- Category
- Article
- ISSN
- 1234-1983
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Previous studies suggest that the relationship between genes and nonsyndromic cleft lip +/- cleft palate (CLP) or cleft palate only (CP) may be modified by the environment. Using data from a population-based case-control study, we examined allelic variants for three genes, i.e., transforming growth
Extensive epidemiological and genetic studies of the cause of oral clefts have demonstrated strong familial aggregation but have failed to yield definitive evidence of any single genetic mechanism. We used the transmission/disequilibrium test (TDT) to investigate the relationship between oral clefts