Recent publications concerning the prevalence of Down syndrome at times of chorionic villus sampling (CVS), amniocentesis and livebirth were reviewed with particular interest in estimates of spontaneous loss of Down syndrome fetuses during pregnancy. Data from several studies were combined to provid
Fetal loss rate after chorionic villus sampling and subsequent amniocentesis
โ Scribed by Brandenburg, H. ;Jahoda, M. G. J. ;Pijpers, L. ;Reuss, A. ;Kleyer, W. J. ;Wladimiroff, J. W.
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 255 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0148-7299
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โฆ Synopsis
Abstract
Here we review a group of 82 patients who underwent both chorionic villus sampling (CVS) and amniocentesis in the same pregnancy during the period May 1984โMay 1988. A fetal loss rate of 2.5% is documented. This is not essentially different from the sum of fetal loss rates following each of the procedures separately (CVS, 1.9%; amniocentesis, 1.0%) established during the same period.
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548 cell cultures and karyotypes obtained by early amniocentesis with filtration technique (EAF) at a mean gestational age of 12Y weeks were compared with 555 obtained by transabdominal chorionic villus sampling (CVS) at a mean gestational age of 11 weeks. The number of abnormal karyotypes, culture
Two pregnancies at risk for the carbohydrate-deficient glycoprotein syndrome Type 1A (CDG1A, phosphomannomutase deficient) were monitored by enzyme and genetic linkage analyses. The index case in both families had a proven deficiency of phosphomannomutase (PMM). An unaffected fetus was predicted in