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Fetal interleukin-1 receptor antagonist gene polymorphism, intra-amniotic interleukin-1β levels, and history of spontaneous abortion

✍ Scribed by Sriram C. Perni; Santosh Vardhana; Sara L. Tuttle; Robin B. Kalish; Stephen T. Chasen; Steven S. Witkin

Book ID: 113427871
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 137 KB
Volume: 191
Category: Article
ISSN: 1097-6868
DOI: 10.1016/j.ajog.2004.05.071

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## Objective: To test if interleukin-1beta (il-1beta), il-1 receptor antagonist (il-1ra), il-4, or il-10 gene polymorphisms could be used as markers of susceptibility or severity in rheumatoid arthritis (ra). ## Methods: The study included 108 patients with early ra followed up for 2 years and 12