FETAL HEPATIC NECROSIS FOLLOWING BLOOD SAMPLING FROM THE INTRAHEPATIC VEIN

✍ Scribed by S. N. STURGISS; C. WRIGHT; J. M. DAVISON; S. C. ROBSON

• Book ID: 101235997
• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 371 KB
• Volume: 16
• Category: Article
• ISSN: 0197-3851
• DOI: 10.1002/(sici)1097-0223(199609)16:9<866::aid-pd957>3.0.co;2-x

✦ Synopsis

Previous reports have suggested that fetal blood sampling from the intrahepatic vein is not associated with significant fetal hepatic injury. We report a case of fetal liver necrosis occurring 24 h following blood sampling from the intrahepatic vein of a fetus with severe growth retardation at 34 weeks. The placenta was in a posterior position, precluding either blood sampling from the placental insertion or placental biopsy. Fetal death occurred in utero within 24 h of the procedure, which was carried out by an experienced operator. At post-mortem the liver appeared normally formed, but the right lobe was diffusely congested, with a well-defined demarcation line between the right and left lobes. Liver histology revealed extensive recent haemorrhagic necrosis of the right lobe.