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Fetal encephalopathy with cerebral calcifications: a case report

✍ Scribed by G. Sabatino; S. Domizio; A. Verrotti; L. A. Ramenghi; P. Pelliccia; G. Morgese

Publisher
Springer
Year
1994
Tongue
English
Weight
511 KB
Volume
10
Category
Article
ISSN
0256-7040

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✦ Synopsis

The authors report a case of a newborn with severe encephalopathy and cerebral calcifications. The newborn was admitted to Neonatal Intensive Care Unit in Chieti at 2 days of age suffering from continuous generalized seizures. He was the child of healthy first-degree cousins. Cerebral ultrasonography showed bilateral ventricular dilatation and an intrathlamic hyperechoic image. Computed tomography and magnetic resonance imaging showed ventricular and corpus callosus hypoplasia, pachygyria, widespread delayed myelination areas, and basal nuclei and periventricular calcifications. All serum and urine analyses showed normal results. In particular, all demyelinizing metabolic diseases were excluded. Based upon these findings, we speculate that this infant may be suffering from fetal encephalopathy with cerebral calcifications.

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