Fetal bilateral renal agenesis, phocomelia, and single umbilical artery associated with cocaine abuse in early pregnancy
✍ Scribed by Maki Kashiwagi; Rabih Chaoui; Thomas Stallmach; Sandra Hürlimann; Urs Lauper; Gundula Hebisch
- Book ID
- 101703743
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 81 KB
- Volume
- 67
- Category
- Article
- ISSN
- 1542-0752
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✦ Synopsis
Abstract
BACKGROUND
Maternal cocaine abuse in pregnancy is associated with complications such as intrauterine growth retardation, abruptio placentae, and preterm delivery.
CASE
We report what is, to our knowledge, the first published observation of fetal bilateral renal agenesis associated with a vascular disruption syndrome comprising upper limb reduction defect and a single umbilical artery following maternal cocaine abuse in early pregnancy.
CONCLUSIONS
This constellation in a fetus aborted at 18 weeks extends the spectrum of complications possibly associated with cocaine abuse in pregnancy. Birth Defects Research (Part A), 2003. © 2003 Wiley‐Liss, Inc.