Fertilisation involving ageing gametes, major birth defects, and Down's syndrome
✍ Scribed by Joe Leigh Simpson; Ron Gray; Alfredo Perez; Patricio Mena; John T Queenan; Michele Barbato; Francesco Pardo; Robert Kambic; Victoria Jennings
- Book ID
- 117280634
- Publisher
- The Lancet
- Year
- 2002
- Tongue
- English
- Weight
- 59 KB
- Volume
- 359
- Category
- Article
- ISSN
- 0140-6736
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Some indirect relationships between contraception failures and offspring with a pathological condition are reviewed, and a causal connection between them is suggested. This hypothesis is supported by the decreasing incidence of Down syndrome (DS) in general in recent years, and the increase among th
We conducted a study to investigate the effect of parity on the following six serum markers used in screening for Down's syndrome, after adjusting them for ethnic group and maternal weight: alpha-fetoprotein (AFP), unconjugated oestriol (uE,), total human chorionic gonadotrophin (hCG), free a-hCG, f