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Fertile females produced by inactivation of an X chromosome of ‘sex-reversed’ mice

✍ Scribed by McLaren, Anne; Monk, Marilyn

Book ID
109729259
Publisher
Nature Publishing Group
Year
1982
Tongue
English
Weight
371 KB
Volume
300
Category
Article
ISSN
0028-0836

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Fertile male mice with three sex chromosomes: Evidence that infertility in XYY male mice is an effect of two Y chromosomes
✍ Patricia A. Hunt; Eva M. Eicher 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 1008 KB

In the mouse XYY males are sterile, presumably because pairing abnormalities resulting from the presence of three sex chromosomes lead to meiotic breakdown. We have produced male mice, designated XYY\*X, that have three sex chromosomes pairing regions but only one intact Y chromosome. Unexpectedly X