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Fenoldopam Inhibits Nuclear Translocation of Nuclear Factor Kappa B in a Rat Model of Surgical Ischemic Acute Renal Failure

✍ Scribed by Natarajan Aravindan; Mohan Natarajan; Andrew D. Shaw

Book ID: 117819713
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 402 KB
Volume: 20
Category: Article
ISSN: 1532-8422
DOI: 10.1053/j.jvca.2005.03.028

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## Abstract We have previously reported that prostaglandin A~1~ (PGA~1~) reduces infarct size in rodent models of focal ischemia. This study seeks to elucidate the possible molecular mechanisms underlying PGA~1~'s neuroprotective effects against ischemic injury. Rats were subjected to permanent mid