Femoral–facial syndrome with malformations in the central nervous system
✍ Scribed by Evelia Leal; Nelly Macı́as-Gómez; Lisa Rodrı́guez; F.Miguel Mercado; Patricio Barros-Núñez
- Book ID
- 114284813
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 187 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0899-7071
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Of 144 patients with the CHARGE association (literature 136, new patients 8), 47 (33%) had either a postmortem examination (30) or computerized axial tomography scan (17) of the head. Twenty-six of 47 (55%) had definite central nervous system (CNS) malformations: arhinencephaly, with or without othe
## Abstract ## BACKGROUND: The Ljungan virus (LV) has been shown to cause central nervous system malformations in laboratory mouse models. The LV has also been associated with intrauterine fetal death in humans. We investigated the presence of LV in a series of human hydrocephaly and anencephaly c