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Feeding problems in merosin-deficient congenital muscular dystrophy

โœ Scribed by J. Philpot; A. Bagnall; C. King; F. Goodwin; V. Dubowitz; F. Muntoni


Book ID
117670738
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
131 KB
Volume
7
Category
Article
ISSN
0960-8966

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Merosin and congenital muscular dystroph
โœ Miyagoe-Suzuki, Yuko; Nakagawa, Masahiro; Takeda, Shin'Ichi ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 181 KB

Merosin (also called as Laminin-2) is an isoform of laminin comprised of the โฃ2, โค1 and โฅ1 chains. In European populations, half of the patients with classical congenital muscular dystrophy have mutations of the LAMA2 gene (6q22-23) and present reduced or absence of laminin โฃ2 chain. This form is ge