Fed-batch hydrocarbon fermentation with colloidal emulsion feed
β Scribed by Fumitake Yoshida; Tsuneo Yamane; Ken-Ichiro Nakamoto
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- English
- Weight
- 545 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0006-3592
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β¦ Synopsis
Abstract
Candida tropicalis was cultured with nβhexadecane, dispersed in water as submicron droplets, as the only carbon substrate; the emulsion being fed continuously into a fermentor containing only an aqueous medium (fedβbatch culture). The results have demonstrated that the organism takes up hydrocarbon accommodated in the aqueous phase as submicron droplets. The cell/substrate yield for the linear growth phase, where growth was limited by the supply of the substrate, was much higher than the yield for the exponential growth phase.
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Based upon the general characteristics of the optimal feed rate profiles presented in an earlier article, efficient computational algorithms have been developed for fedbatch fermentation processes described by four or less mass balance equations. These algorithms make computations of optimal substra