Feather formation in heterotopically grafted terminal parts of the leg bud in chicken embryos
✍ Scribed by Amprino, Rodolfo ;Camosso, Maria
- Publisher
- John Wiley and Sons
- Year
- 1959
- Tongue
- English
- Weight
- 992 KB
- Volume
- 142
- Category
- Article
- ISSN
- 0022-104X
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✦ Synopsis
Basic data on the development. of enibryonic feathers ~7 e r e offered by the descriptive work of Davies (1889)' Kuhn ( '33) ' Holmes ('35), Gerber ('39)' Watterson ('42) and Gofl ( '49). Thc first cxperimental approach to the problem of the dcvelopmental role played by the ectodermal and mesodermal constituents of feather primordia was successfully carried out by Saunders ( '47, '5-1)' Cairns ('51, '58)' Saunders and Cairns ('54) and Saunders, Gasseling and Cairns ('55). These researches showed that the mesoderm initiates the formation of feathers through an induction exerted on the overlying ectoderm. Even more recently the analysis of the interrelationships between mesenchyme and ectoderm in feather germ formation was accomplished in vitro by Sengcl ('56 to '58) in a remarkable series of explantation experiments.
Saunders ('51) grafted isolates from the apical region of the hind-limb bud freed of ectoderm dircctly under the ectodermal apical ridge of the wing anlage in 3Yz to 4-day embryos. Scales, papillae and nails formed from the ectoderni of the wing tip which in normal development gives rise to feathers. Feather germs characteristic of the femoral tract developed in the uppcr arm region when blocks of mesoderm from the dorsal region of the wing bud were replaced by isolates of mesoderm from the proximal portion of the hindlimb bud (Saundcrs, '47; Cairns and Saundcrs, '54). It was
PRESS OF THE WISTAB INSTITUTE OR AXATOMY A N D BIOLOGY