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Feasibility of Using a Bone-Targeted, Macromolecular Delivery System Coupled with Prostaglandin E1to Promote Bone Formation in Aged, Estrogen-Deficient Rats

✍ Scribed by S. C. Miller; H. Pan; D. Wang; B. M. Bowman; P. Kopečková; J. Kopeček

Book ID
106493545
Publisher
Springer US
Year
2008
Tongue
English
Weight
254 KB
Volume
25
Category
Article
ISSN
0724-8741

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✍ Masaki Fujieda; Michiaki Kiriu; Shigeki Mizuochi; Ken-ichi Hagiya; Hiroyuki Kane 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 363 KB 👁 2 views

The effects of prostaglandin E 2 (PGE 2 ) on the parameters for proliferation and differentiation were studied in calvarial osteoblast-like cells isolated from rats of various ages. In cells not treated with PGE 2 , it was found that mineralized bone nodule (BN) formation, alkaline phosphatase (ALP)