Feasibility of prehospital r-TPA therapy in chest pain patients
β Scribed by Tom P Aufderheide; William C Haselow; Gail E Hendley; Nancy A Robinson; Lisa Armaganian; Kathleen M Hargarten; David W Olson; Verena T Valley; Harlan A Stueven
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 425 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1097-6760
No coin nor oath required. For personal study only.
β¦ Synopsis
Study objective:
The purpose of this study was to determine the number of eligible prehospital thrombolytic candidates and to estimate the potential time saved if field thrombolysis had been initiated in a series of prehespital chest pain patients.
Design and setting: Prehospita112-lead ECGs were obtained by paramedics during initial evaluation of chest pain patients and stored in the computerized ECG. Prehospital 12-lead ECGs, prehospitat charts, and hospital charts then were reviewed retrospectively for final hospital diagnosis, prehospital and emergency department times, and historical exclusion criteria for prehospital treatment with recombinant tissue-type plasminogen activator (r-TPA).
Type of participants: One hundred fifty-seven stable adult prehospital patients with a chief complaint of nontraumatic chest pain were enrolled. Six patients were excluded. Two had unretrievable 12-lead ECGs, and four refused paramedic transport and thus provided no further data. There were complete data on 151 patients making up the final study population. APRIL1992 21:4 ANNALS OF EMERGENCY MEDICINE 379/41 r-TPA Aufderheide et al Conclusion: Prehospita112-lead ECGs provide an ECG diagnosis 40 to 50 minutes earlier than ED ECGs. However, with current exclusion criteria, the number of prehospital r-TPA candidates is limited.
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