## Ethics of placebo-controlled trials in depression Some believe that introducing a placebo control into an antidepressant drug trial means that ill patients are being unnecessarily deprived of treatment. As a result, many clinicians and ethical committees are opposed to the use of such trial met
Feasibility of placebo-controlled clinical trials of antipsychotic compounds in Europe
β Scribed by Wolfgang W. Fleischhacker; Tom Burns; European Group for Research in Schizophrenia
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 22 KB
- Volume
- 162
- Category
- Article
- ISSN
- 0033-3158
No coin nor oath required. For personal study only.
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Sixty-seven patients meeting DSM-III-R criteria for schizophrenia who had been eligible for a placebo controlled trial of an antipsychotic preparation were followed up at 9 months to examine whether a variety ofsocio-demographic, illness, treatment and compliance variables were associated with conse
## Abstract ## Objective Schizophrenia is a multifaceted illness with positive, negative and cognitive symptom domains. Standard treatments often focus on positive symptoms and may not adequately relieve other symptoms. Previous studies have suggested a role for mirtazapine in schizophrenia, parti