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Feasibility of Developing a Neural Network for Prediction of Human Pharmacokinetic Parameters from Animal Data

โœ Scribed by Ajaz S. Hussain; Robert D. Johnson; Nimish N. Vachharajani; Wolfgang A. Ritschel


Book ID
110379483
Publisher
Springer US
Year
1993
Tongue
English
Weight
789 KB
Volume
10
Category
Article
ISSN
0724-8741

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The aim of the study reported here was to develop a regression equation for predicting oral clearance of various kinds of drugs in humans using experimental data from rats and dogs and molecular structural parameters. The data concerning the oral clearance of 87 drugs from rats, dogs, and humans wer