## Abstract ## Purpose To evaluate aortic elasticity with MRI on young asymptomatic individuals with mutation of the smooth muscle myosin heavy chain in whom aortic enlargement is not present. ## Materials and Methods Aortic compliance, aortic distensibility, and pulse wave velocity (PWV) were s
Feasibility of aortic pulse pressure and pressure wave velocity MRI measurement in young adults
✍ Scribed by Eric Laffon; Roger Marthan; Michel Montaudon; Valérie Latrabe; François Laurent; Dominique Ducassou
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 206 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1053-1807
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✦ Synopsis
Abstract
Purpose
To investigate the feasibility of assessing, noninvasively, aortic pulse pressure (APP) and pulse wave velocity (PWV) in the ascending aorta of young adults by means of velocity‐encoded magnetic resonance (MR) imaging.
Materials and Methods
In a series of 11 healthy volunteers, velocity‐encoded MR imaging provided pairs of magnitude and phase‐contrast images. Blood flow velocity and aortic cross‐sectional area (CSA) were determined with a 30‐msec temporal resolution. A model analysis revealed that variation in aortic CSA and in maximal blood flow velocity throughout systole could be used to estimate APP and, hence, to derive PWV by means of two different methods.
Results
Mean ± SD values of the APP for the series were 54.2 ± 16.4 mmHg (range 32.2–84.1 mmHg). The ascending aortic PWV mean ± SD values were 5.03 ± 1.10 m/second and 5.37 ± 1.23 m/second according to the two methods, and both estimates were not significantly different (95% confidence level).
Conclusion
These results are in agreement with previously published data, suggesting that APP and PWV can be determined, noninvasively, in young adults using MRI. J. Magn. Reson. Imaging 2005;21:53–58. © 2004 Wiley‐Liss, Inc.
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