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Feasibility and efficacy of bone tissue engineering using human bone marrow stromal cells cultivated in serum-free conditions

✍ Scribed by Hideki Agata; Nobukazu Watanabe; Yumiko Ishii; Noriyuki Kubo; Satoshi Ohshima; Mika Yamazaki; Arinobu Tojo; Hideaki Kagami

Book ID: 116298354
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 721 KB
Volume: 382
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2009.03.023

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## Abstract Porous 3D structures from mineralized collagen were fabricated applying a procedure in which collagen fibril reassembly and precipitation of nanocrystalline hydroxyapatite (HA) occur simultaneously. The resulting matrices were evaluated __in vitro__ with respect to their suitability as