Fearful behavior, body size, and serum IGF-I levels in nervous and normal pointer dogs

Elevated serum levels of IGF-1 are suffi

Elevated serum levels of IGF-1 are sufficient to establish normal body size and skeletal properties even in the absence of tissue IGF-1

✍ Sebastien Elis; Hayden-William Courtland; Yingjie Wu; Clifford J Rosen; Hui Sun; 📂 Article 📅 2010 🏛 American Society for Bone and Mineral Research 🌐 English ⚖ 338 KB

Use of recombinant insulin-like growth factor 1 (IGF-1) as a treatment for primary IGF-1 deficiency in children has become increasingly common. When untreated, primary IGF-1 deficiency may lead to a range of metabolic disorders, including lipid abnormalities, insulin resistance, and decreased bone d