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FDA Recommendations for Preclinical Testing of Gonadotropin Releasing Hormone (GnRH) Analogues

โœ Scribed by K.L. Raheja; A. Jordan

Book ID
115646406
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
499 KB
Volume
19
Category
Article
ISSN
0273-2300

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Gonadotropin-releasing hormone (GnRH) stimulates the release and synthesis of gonadotropin hormones (GtH) and is the key regulator of reproduction. The present study was carried out to design a potent GnRH analogue containing Tyr(OMe) at position 5 and a D-amino acid at position 6. This was based on