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Fcγ receptors: structure, function and role as genetic risk factors in SLE

✍ Scribed by Li, X; Ptacek, T S; Brown, E E; Edberg, J C


Book ID
109852904
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
199 KB
Volume
10
Category
Article
ISSN
1466-4879

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## Objective: Fcγ receptor type iib (fcγriib) is a major negative regulator of b cells, and the lack of fcγriib expression has been reported to induce systemic lupus erythematosus (sle) in mice of the c57bl/6 (b6) genetic background. the 129 strain-derived sle16 locus on the telomeric region of chr