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FCCP modulation of Ca2+ oscillation in rat megakaryocytes

โœ Scribed by Chikako Uneyama; Hisayuki Uneyama; Michihito Takahashi; Norio Akaike


Book ID
113398683
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
362 KB
Volume
268
Category
Article
ISSN
0922-4106

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In rat pituitary gonadotropes, gonadotropin-releasing hormone (GnRH) stimulates rhythmic release of Ca2+ from stores sensitive to inositol 1,4,5-trisphosphate [Ins(1,4,5)P3], which in turn induces an oscillatory activation of apamin-sensitive Ca2+-activated K+ current, IK(Ca). Since GnRH also activa