FC2 5α-reductase inhibitors: Synthesis and structure-activity studies on new non-steroidal compounds
✍ Scribed by Göhring, S.; Reichert, M.; Hartmann, R.W.
- Book ID
- 121772670
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 131 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0928-0987
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The synthesis and biological evaluation of 4-(4-(alkyl- and phenylaminocarbonyl)benzoyl)benzoic acids (4a-4d) as non-steroidal inhibitors of steroid 5 alpha-reductase are described. The compounds were tested in vitro for inhibitory activity toward rat and human 5 alpha-reductase isozymes 1 and 2 at