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Fatty acid–spermine conjugates as DNA carriers for nonviral in vivo gene delivery

✍ Scribed by Viola, J R; Leijonmarck, H; Simonson, O E; Oprea, I I; Frithiof, R; Purhonen, P; Moreno, P M D; Lundin, K E; Strömberg, R; Smith, C I E

Book ID
109855213
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
491 KB
Volume
16
Category
Article
ISSN
0969-7128

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✍ Ronny Martien; Brigitta Loretz; Marlene Thaler; Sayeh Majzoob; Andreas Bernkop-S 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 276 KB

## Abstract Regarding safety concerns, nonviral gene delivery vehicles that have the required efficiency and safety for use in human gene therapy are being widely investigated. The aim of this study was to synthesize and evaluate a thiolated chitosan to improve the efficacy of oral gene delivery sy