Aff the dImethylene-inferrupied Fethyl octadecadiynoates have been synthesised and the gas-liquid chromatographic behaviour of these isomers was studied on polar [Carbowax 2OM, FFAP, DEGA, DEGS and War IOC (rcceniIy renamed as Apolw tOc)f, semi-poIar (XE-60) and non-p&x (SE-IO, OV-101 and Apiezon L) statiunary phases. The possibility of identification and separation of these isomers is discussed. The LW.'~ isomer was found to decompose on most polar phases and the d-*0" isomer co&d not be eluted from the Carbowax 20M phase.
Christie and Holman synthesised the complete series of methylene-interrupted c~~,~is-octade~dienois: acids2 and studied the physicaal'-F and some biologicz@ proptrties of these isomers in detail. The occurrence in nature of several dimethyleneioterrupted octadecadienoic acid isomersh-1L Ied us to prepare the complete series of tEe f,S-diacet;yIenic Ci8 acids to study their physical, chemical, and biologica! proper-53.
Afi dimethylene-interrupted octadecadiynoic acids were readily synthesised b weI1 established methods't. Fig. f o&ines the various synthesis routes. Of the p I ssibie twelve isomers on@ four (46~JOq 47n*11n$ 4m*s'c and 4 i20J5G) were previously S :tfie&edlZ-14 .