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Fatty acid transporters involved in the palmitate and oleate induced insulin resistance in primary rat hepatocytes

✍ Scribed by Chabowski, A.; Żendzian-Piotrowska, M.; Konstantynowicz, K.; Pankiewicz, W.; Mikłosz, A.; Łukaszuk, B.; Górski, J.

Book ID
119826602
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
411 KB
Volume
207
Category
Article
ISSN
1748-1708

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## Abstract Palmitate negatively affects insulin secretion and apoptosis in the pancreatic β‐cell. The detrimental effects are abolished by elongating and desaturating the fatty acid into oleate. To investigate mechanisms of how the two fatty acids differently affect β‐cell function and apoptosis,