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Fatty acid synthase inhibitor orlistat induces apoptosis in T cell lymphoma: Role of cell survival regulatory molecules

โœ Scribed by Shiva Kant; Ajay Kumar; Sukh Mahendra Singh


Book ID
119193940
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
1007 KB
Volume
1820
Category
Article
ISSN
0304-4165

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Chemical inhibitors of fatty acid synthase (FAS) inhibit growth and induce apoptosis in several cancer cell lines in vitro and in tumor xenografts in vivo. Recently the green tea component epigallocatechin-3-gallate (EGCG) was shown to act as a natural inhibitor of FAS in chicken liver extracts. Her