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Fatty acid hydrazides in heterocyclic synthesis: Synthesis of 1,2-diazepine and pyridazine derivatives

✍ Scribed by Magdi E. A. Zaki; Elham A. A. Yousef; Abu Zeid A. Hassanien


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
174 KB
Volume
18
Category
Article
ISSN
1042-7163

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✦ Synopsis


Abstract

1,2‐Diazepinone derivatives 6a–d, 8a,b, and 10a–c were synthesized from the reaction of olefines carrying EWG as ethoxymethylene malononitrile, ethoxymethylene cyanoacetate, and tetracyanoethylene with 1a–f respectively. Also, 5‐alkyl‐6‐oxotetrahydropyridazine‐4,4‐dicarboxylate derivatives 12a–c were afforded via the reaction of 1d–f with diethyl ethoxymethylene malonate. © 2007 Wiley Periodicals, Inc. Heteroatom Chem 18:259–264, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20294


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