Fatty acid and aldehyde changes in choline- and ethanolamine-containing phospholipids in the white matter of multiple sclerosis brains
โ Scribed by G. Arnetoli; A. Pazzagli; L. Amaducci
- Book ID
- 111165683
- Publisher
- John Wiley and Sons
- Year
- 1969
- Tongue
- English
- Weight
- 156 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0022-3042
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## Abstract Oxidative stress has been implicated in the pathophysiology of multiple sclerosis (MS). Increased levels of reactive oxygen species (ROS) derived from infiltrating macrophages and microglial cells have been shown to reduce the levels of endogenous antioxidants and to cause the oxidation
A micromethod for the investigation of the fatty acid composition of sphingomyelin in presented. In the cerebral white matter of 17 normal adult brains, analyzed for reference, the predominant fatty acids are C 18:0 and C 24:1. Our results are in agreement with those of other authors. Short chained